No, not really. Both cars have PP-Performance tunes so it is not like the tuner has something at stake in this race either way. The Panamera Turbo (wow those underbody lights are German rice! Is Fast and the Furious 1 still popular overseas?) gets a healthy lead. It almost seems as if the M5 was in the wrong gear with how right off the bat the Panamera gets a couple car lengths.
The M5 starts to reel it in at 130 miles per hour and by 170 it puts car lengths on the Panamera Turbo. Traction should not be an issue for the F10 M5 at these starting speeds and at this power level so why the M5 gets pulled early is anyone's guess.
Regardless, the M5 shows a significant top end advantage and on the highway a tuned (and really even stock F10 M5) has nothing to fear from a Panamera Turbo with a tune. Porsche's new V8 engine family can't come soon enough.